Photocatalyic Appel reaction enabled by copper-based complexes in continuous flow

Beilstein Journal of Organic Chemistry

Shawn K. Collins¹  Jean-Christophe Grenier-Petel¹  Clémentine Minozzi¹  Shawn Parisien-Collette¹ 

[1] Department of Chemistry and Centre for Green Chemistry and Catalysis, Université de Montréal, CP 6128 Station Downtown, Montréal, Québec, H3C 3J7, Canada;

关键词: Appel;    continuous flow;    copper;    halides;    photocatalysis;   

DOI  :  10.3762/bjoc.14.251

来源: DOAJ

【 摘 要 】

A copper-based photocatalyst, Cu(tmp)(BINAP)BF4, was found to be active in a photoredox Appel-type conversion of alcohols to bromides. The catalyst was identified from a screening of 50 complexes and promoted the transformation of primary and secondary alcohols to their corresponding bromides and carboxylic acids to their anhydrides. The protocol was also amendable and optimized under continuous flow conditions.

【 授权许可】

Unknown