Effectiveness of Internet-and Mobile-Based Cognitive Behavioral Therapy to Reduce Suicidal Ideation and Behaviors: Protocol for a Systematic Review and Meta-Analysis of Individual Participant Data

International Journal of Environmental Research and Public Health

Matthias Domhardt¹  Lena Steubl¹  Ad Kerkhof²  Pim Cuijpers²  Rebekka Büscher³  Lasse B. Sander³  Philipp Doebler⁴  Marie Beisemann⁴ 

[1] Department of Clinical Psychology and Psychotherapy, Ulm University, 89069 Ulm, Germany;Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, 1081 BT Amsterdam, The Netherlands;Department of Rehabilitation Psychology and Psychotherapy, Albert-Ludwigs-University of Freiburg, 79106 Freiburg, Germany;Department of Statistics, TU Dortmund University, 44227 Dortmund, Germany;

关键词: individual participant data meta-analysis;    review;    suicidal ideation;    suicide;    internet-based;    mobile-based;   

DOI  :  10.3390/ijerph17145179

来源: DOAJ

【 摘 要 】

Internet- and mobile-based cognitive behavioral therapy (iCBT) might reduce suicidal ideation. However, recent meta-analyses found small effect sizes, and it remains unclear whether specific subgroups of participants experience beneficial or harmful effects. This is the study protocol for an individual participant meta-analysis (IPD-MA) aiming to determine the effectiveness of iCBT on suicidal ideation and identify moderators. We will systematically search CENTRAL, PsycINFO, Embase, and Pubmed for randomized controlled trials examining guided or self-guided iCBT for suicidality. All types of control conditions are eligible. Participants experiencing suicidal ideation will be included irrespective of age, diagnoses, or co-interventions. We will conduct a one-stage IPD-MA with suicidal ideation as the primary outcome, using a continuous measure, reliable improvement and deterioration, and response rate. Moderator analyses will be performed on participant-, study-, and intervention-level. Two independent reviewers will assess risk of bias and the quality of evidence using Cochrane’s Risk of Bias Tool 2 and GRADE. This review was registered with OSF and is currently in progress. The IPD-MA will provide effect estimates while considering covariates and will offer novel insights into differential effects on a participant level. This will help to develop more effective, safe, and tailored digital treatment options for suicidal individuals.

【 授权许可】

Unknown