Korean research project on the integrated exposure assessment of hazardous substances for food safety

Environmental Health and Toxicology

Kyung Su Park¹  Kwang-Geun Lee²  Se Young Oh³  Seok-Joon Sohn⁴  Jung-Duck Park⁵  Yong Dae Kim⁶  Ji-Ae Lim⁷  Ho-Jang Kwon⁷  Mina Ha⁷  Young-Seoub Hong⁸  Sang-Ah Lee⁹  Ho Kim^1,10  Jeong Seon Kim^1,11  Myung Sil Hwang^1,12  Sangil Jun^1,13  Heesoo Pyo^1,14 

[1]Advanced Analysis Center, Korea Institute of Science and Technology, Seoul, Korea

[2]Department of Food Science and Biotechnology, Dongguk University, Seoul, Korea

[3]Department of Food and Nutrition, Kyung Hee University College of Human Ecology, Seoul, Korea

[4]Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Korea

[5]Department of Preventive Medicine, Chung-Ang University College of Medicine, Seoul, Korea

[6]Department of Preventive Medicine, Chungbuk National University College of Medicine, Cheongju, Korea

[7]Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea

[8]Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea

[9]Department of Preventive Medicine, Kangwon National University School of Medicine, Chuncheon, Korea

[10]Department of Public Health Statistics, Graduate School of Public Health, Seoul National University, Seoul, Korea

[11]Division of Cancer Epidemiology and Prevention, National Cancer Center, Goyang, Korea

[12]Food Risk Analysis Division, National Institute of Food and Drug Safety Evaluation, Cheongwon, Korea

[13]Korea Institute of Environment and Health, Seoul, Korea

[14]Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul, Korea

关键词: Food intake;    Hazardous substances;    Heavy metal;    Integrated dietary exposure assessment;    Survey design;   

DOI  :  10.5620/eht.e2015004

来源: DOAJ

【 摘 要 】

Objectives: This survey was designed to conduct the first nationwide dietary exposure assessment on hazardous substances including the intakes of functional food and herbal medicine. In this paper, we introduced the survey design and the results of the dietary exposure status and internal exposure levels of lead (Pb), cadmium (Cd), and mercury (Hg). Methods: We selected 4867 subjects of all ages throughout Korea. We conducted a food survey, dietary survey, biomonitoring, and health survey. Results: Pb and Cd were the highest (median value) in the seaweed (94.2 μg/kg for Pb; 594 μg/kg for Cd), and Hg was the highest in the fish (46.4 μg/kg). The dietary exposure level (median value) of Pb was 0.14 μg/kg body weight (bw)/d, 0.18 μg/kg bw/d for Cd, and 0.07 μg/kg bw/d for Hg. Those with a blood Pb level of less than 5.00 μg/dL (US Centers for Disease Control and Prevention, reference value for those 1 to 5 years of age) were 99.0% of all the subjects. Those with a blood Cd level with less than 0.30 μg/L (German Federal Environmental Agency, reference value for non-smoking children) were 24.5%. For those with a blood Hg level with less than 5.00 μg/L (human biomonitoring I, references value for children and adults, German Federal Environmental Agency) was 81.0 % of all the subjects. Conclusions: The main dietary exposure of heavy metals occurs through food consumed in a large quantity and high frequency. The blood Hg level and dietary exposure level of Hg were both higher than those in the European Union.

【 授权许可】

Unknown