期刊论文详细信息
BMC Geriatrics
Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative Study
Jens Gaedeke1  Markus van der Giet1  Martin K. Kuhlmann2  Peter Martus3  Antonios Douros4  Natalie Ebert5  Elke Schaeffner5  Nina Mielke5  Dörte Huscher5 
[1] Departement of Nephrology and Medical Intensive Care, Charité – Universitätsmedizin Berlin;Department of Nephrology, Vivantes Klinikum im Friedrichshain;Institute of Clinical Epidemiology and Medical Biostatistics, Eberhard Karls-University;Institute of Clinical Pharmacology and Toxicology, Charité – Universitätsmedizin Berlin;Institute of Public Health, Charité Universitätsmedizin Berlin;
关键词: Older adults;    Medication;    Polypharmacy;    Potentially inappropriate medication;    Prescription drugs;    Over-the-counter drugs;   
DOI  :  10.1186/s12877-020-1430-6
来源: DOAJ
【 摘 要 】

Abstract Background Older adults have the highest drug utilization due to multimorbidity. Although the number of people over age 70 is expected to double within the next decades, population-based data on their medication patterns are scarce especially in combination with polypharmacy and potentially inappropriate medication (PIM). Our objective was to analyse the frequency of polypharmacy, pattern of prescription (PD) and over-the-counter (OTC) drug usage, and PIMs according to age and gender in a population-based cohort of very old adults in Germany. Methods Cross-sectional baseline data of the Berlin Initiative Study, a prospective cohort study of community-dwelling adults aged ≥70 years with a standardized interview including demographics, lifestyle variables, co-morbidities, and medication assessment were analysed. Medication data were coded using the Anatomical Therapeutic Chemical (ATC) classification. Age- and sex-standardized descriptive analysis of polypharmacy (≥5 drugs, PD and OTC vs. PD only and regular and on demand drugs vs regular only), medication frequency and distribution, including PIMs, was performed by age (

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