Effectiveness of a Serious Game for Cognitive Training in Chronic Stroke Survivors with Mild-to-Moderate Cognitive Impairment: A Pilot Randomized Controlled Trial

Applied Sciences

Hee-Tae Jung¹  SunghoonIvan Lee¹  Tenzin Nanglo¹  Jean-Francois Daneault²  Yangsoo Kim³  Byeongil Kim⁴  Hyunsuk Lee⁴ 

[1] College of Information and Computer Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA;Department of Rehabilitation and Movement Sciences, Rutgers University, New Brunswick, NJ 07107, USA;Heeyeon Rehabilitation Hospital, Changwon 51420, Gyeongsangnam-do, Korea;Woorisoft, Daegu 42781, Korea;

关键词: serious games;    mobile games;    cognitive impairment;    cognitive rehabilitation;    stroke survivors;    chronic stage;   

DOI  :  10.3390/app10196703

来源: DOAJ

【 摘 要 】

Previous cognitive training games for stroke survivors required the close supervision of therapists. We aim to demonstrate the preliminary therapeutic effectiveness of Neuro-World, serious mobile games for cognitive training, in chronic stroke survivors with mild-to-moderate cognitive impairment without therapist supervision. For that, we conducted a randomized, controlled clinical trial at a single long-term care rehabilitation center with 50 stroke survivors in the chronic stage with mild-to-moderate cognitive impairment. Participants were randomized to standard medical care (n = 25) or standard medical care plus administration of Neuro-World (n = 25) over 12 weeks. A two-way mixed model ANOVA and Tukey’s post hoc tests identified significant differences in outcomes between the experimental and the control groups at post-intervention but not at baseline. Within the experimental group, there were statistically significant improvements in all the outcomes except for the language category of the Mini-Mental State Examination and Digit Forward Span. The improvements were clinically significant for the total Mini-Mental State Examination, Digit Forward Span, and Digit Backward Span. Within the control group, there were no improvements in any of the outcomes. The practice of Neuro-World led to significant improvements in cognitive function and marginal mitigation of depressive symptoms in chronic stroke survivors with mild-to-moderate cognitive impairment.

【 授权许可】

Unknown