Impact of probiotics and prebiotics targeting metabolic syndrome

Journal of Functional Foods

Egidio Dorea Lima¹  Raquel Bedani²  Susana Marta Isay Saad³  Douglas Xavier-Santos³ 

[1] Department of Civil, Chemical and Environmental Engineering, University of Genoa, Pole of Chemical Engineering, Via Opera Pia 15, 16145 Genoa, Italy;Food Research Center, University of São Paulo, São Paulo, Brazil;Department of Biochemical and Pharmaceutical Technology, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, B16, 05508-000 São Paulo, SP, Brazil;

关键词: Probiotics;    Functional foods;    Intestinal microbiota;    Dysbiosis;    Metabolic disorders;   

DOI  :  

来源: DOAJ

【 摘 要 】

Several studies are contributing to the better understanding of the impact of probiotics and prebiotics on the modulation of the intestinal microbiota and subsequent effects on the host’s health. This review aimed to discuss the results of studies using different experimental models to evaluate the impact of the supplementation with probiotics and/or prebiotics on the different risk factors related to metabolic syndrome (MetS). A better understanding of the daily supplementation of probiotics and prebiotics regarding the mechanisms involved in the modulation of the intestinal microbiota and the immune system of patients suffering from this metabolic disorder is necessary to establish the efficiency of possible biomarkers that could contribute towards a health claim. Although the results might be promising, the functionality of probiotics and prebiotics on the intestinal microbiota and its relationship with MetS are still poorly understood to indicate their consumption for prevention and management of MetS in clinical practice.

【 授权许可】

Unknown