Aging and immunoglobulin isotype patterns in oral tolerance

Brazilian Journal of Medical and Biological Research

关键词: oral tolerance;    aging;    isotypes;    gut;    mucosa;   

DOI  :  10.1590/S0100-879X1998000100005

来源: DOAJ

【 摘 要 】

In the present review we address oral tolerance as an important biological phenomenon and discuss how it is affected by aging. Other factors such as frequency of feeding and previous digestion of the antigen also seem to influence the establishment of oral tolerance. We also analyze immunoglobulin isotypes of specific antibodies formed by tolerant and immunized animals of different ages submitted to different conditions of oral antigen administration. Isotypic patterns were studied as a parameter for assessing the pathways of B and T cell interactions leading to antibody production

【 授权许可】

Unknown