Practical Synthesis of Ethynyl(phenyl)-λ3-Iodane Using Calcium Carbide as an Ethynyl Group Source

Frontiers in Chemistry

Masanobu Uchiyama¹  Takahiro Hashishin²  Kazunori Miyamoto²  Taisei Osawa² 

[1] Cluster of Pioneering Research (CPR), Advanced Elements Chemistry Laboratory, RIKEN, Saitama, Japan;Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan;Research Initiative for Supra-Materials (RISM), Shinshu University, Ueda, Japan;

关键词: hypervalent;    iodine;    stannane;    calcium carbide;    ethynyl;   

DOI  :  10.3389/fchem.2020.00012

来源: DOAJ

【 摘 要 】

Stannylation of calcium carbide followed by Sn–hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-λ3-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions.

【 授权许可】

Unknown