期刊论文详细信息
Molecules | |
A Novel Synthesis of Fused Uracils: Indenopyrimidopyridazines, Pyrimidopyridazines, and Pyrazolopyrimidines for Antimicrobial and Antitumor Evalution | |
Fatimah Agili1  Samar El-Kalyoubi2  | |
[1] Chemistry Department, Faculty of Science (Female Section), Jazan University, Jazan 82621, Saudi Arabia;Department of Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City 11651, Cairo, Egypt; | |
关键词: 6-chlorouracil; 6-hydrazinyluracils; ninhydrin; isatin indenopyrimidopyridazines; pyrrolopyrimidines; pyrimidopyridazines; | |
DOI : 10.3390/molecules21121714 | |
来源: DOAJ |
【 摘 要 】
A variety of different compounds of fused uracils were prepared simply by the heating of 6-hydrazinyl-1-methyl-, 6-hydrazinyl-1-propyl-, or 6-hydrazinyl-1,3-dipropyluracil under reflux with ninhydrin, isatin, benzylidene malononitrile, benzylylidene ethyl cyanoacetate, benzil, and phenacyl bromide derivatives. The newly synthesized compounds were completely screened for antimicrobial and antitumor activity.
【 授权许可】
Unknown