Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsisthaliana

iScience

Jin Hoon Won¹  Kyounghee Lee²  Hong Gil Lee³  Pil Joon Seo³  Yee-Ram Choi³ 

[1] Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, South Korea;Department of Biological Sciences, Sungkyunkwan University, Suwon 16419, South Korea;Department of Chemistry, Seoul National University, Seoul 08826, South Korea;

关键词: Chronobiology;    Plant Biology;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: Brassinosteroids (BRs) regulate a variety of physiological processes in plants via extensive crosstalk with diverse biological signaling networks. Although BRs are known to reciprocally regulate circadian oscillation, the molecular mechanism underlying BR-mediated regulation of circadian clock remains unknown. Here, we demonstrate that the BR-activated transcription factor bri1-EMS-SUPPRESSOR 1 (BES1) integrates BR signaling into the circadian network in Arabidopsis. BES1 repressed expression of CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) at night by binding to their promoters, together with TOPLESS (TPL). The repression of CCA1 and LHY by BR treatment, which occurred during the night, was compromised in bes1-ko and tpl-8 mutants. Consistently, long-term treatment with BR shortened the circadian period, and BR-induced rhythmic shortening was impaired in bes1-ko and tpl-8 single mutants and in the cca1-1lhy-21 double mutant. Overall, BR signaling is conveyed to the circadian oscillator via the BES1/TPL-CCA1/LHY module, contributing to gating diurnal BR responses in plants.

【 授权许可】

Unknown