Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

Beilstein Journal of Nanotechnology

Valeriy P. Antonovich¹  Inna I. Leonenko¹  Yuliya V. Scrypynets¹  Alla V. Yegorova¹  Anton L. Popov²  Nelly R. Popova²  Vladimir K. Ivanov³  Alexander Ye. Baranchikov³  Mykhailo M. Guzyk⁴  Nadezhda M. Zholobak⁵  Alexander B. Shcherbakov⁵ 

[1] Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa 65080, Ukraine;Institute of Theoretical and Experimental Biophysics, Pushchino 142290, Russia;Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Moscow 119991, Russia;Palladin Institute of Biochemistry NAS of Ukraine, Kyiv 01601, Ukraine;Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv 03680, Ukraine;

关键词: cell culture;    citric acid;    layer-by-layer (LbL)-microcapsules;    luminescence;    organic dots (O-dots);    staining;    toxicity;   

DOI  :  10.3762/bjnano.7.182

来源: DOAJ

【 摘 要 】

Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated.

【 授权许可】

Unknown