Incidence, mortality, risk factors, and trends for Hodgkin lymphoma: a global data analysis

Journal of Hematology & Oncology

NCD Global Health Research Group, Association of Pacific Rim Universities (APRU)¹  Don Eliseo Lucero-Prisno²  Zhi-Jie Zheng³  Veeleah Lok⁴  Mellissa Withers⁵  Lin Zhang⁶  Wanghong Xu⁷  Martin C. S. Wong⁸  Junjie Huang⁸  Wing Sze Pang⁸  Edmar Elcarte⁹ 

[1] ;Department of Global Health and Development, London School of Hygiene and Tropical Medicine;Department of Global Health, School of Public Health, Peking University;Department of Global Public Health, Karolinska Institute, Karolinska University Hospital;Department of Population and Health Sciences, USC Institute On Inequalities in Global Health, APRU Global Health Program, Keck School of Medicine of USC, University of Southern California;School of Population and Global Health, The University of Melbourne;School of Public Health, Fudan University;The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong;University of the Philippines;

关键词: Hodgkin lymphoma;    Incidence;    Mortality;    Risk factors;    Temporal trend;   

DOI  :  10.1186/s13045-022-01281-9

来源: DOAJ

【 摘 要 】

Abstract Background Hodgkin lymphoma is a lymphatic malignancy commonly found in cervical lymph nodes. This study evaluated the worldwide incidence, mortality, associated risk factors, and temporal trends of Hodgkin lymphoma by sex, age, and country. Methods The age-standardised Hodgkin lymphoma incidence and mortality were retrieved from the GLOBOCAN, CI5 volumes I-XI, WHO mortality database, the NORDCAN and SEER Program. The age-standardised prevalence of smoking, alcohol drinking, obesity, and hypertension was also extracted for each country. Trends were tested using Average Annual Percentage Change (AAPC) from Joinpoint regression analysis. Results The Hodgkin lymphoma incidence and mortality were 0.98 and 0.26 per 100,000 in 2020. A higher incidence was observed in high-income countries, while higher mortality was found in low-income countries. Incidence and mortality were associated with GDP per capita, prevalence of smoking, obesity, and hypertension at the population level. Despite the decreasing mortality trend, there was an increasing incidence, especially among females, younger population, and subjects from Asian countries. Conclusions There was an increasing trend in Hodgkin lymphoma incidence, especially among subjects who were female, younger population, and from Asian countries. Further studies are needed to investigate the reasons for these epidemiologic trends.

【 授权许可】

Unknown