Plasmonic Nanomaterials for Colorimetric Biosensing: A Review

Chemosensors

Maria De Luca¹  Adriano Acunzo¹  Raffaele Velotta¹  Daniele Marra¹  Emanuela Scardapane¹  Antonio Minopoli² 

[1] Department of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, Italy;Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany;

关键词: colorimetric biosensors;    plasmonics;    point-of-care;    nanostructured substrates;    colloidal solutions;    nanozymes;   

DOI  :  10.3390/chemosensors10040136

来源: DOAJ

【 摘 要 】

In the last few decades, plasmonic colorimetric biosensors raised increasing interest in bioanalytics thanks to their cost-effectiveness, responsiveness, and simplicity as compared to conventional laboratory techniques. Potential high-throughput screening and easy-to-use assay procedures make them also suitable for realizing point of care devices. Nevertheless, several challenges such as fabrication complexity, laborious biofunctionalization, and poor sensitivity compromise their technological transfer from research laboratories to industry and, hence, still hamper their adoption on large-scale. However, newly-developing plasmonic colorimetric biosensors boast impressive sensing performance in terms of sensitivity, dynamic range, limit of detection, reliability, and specificity thereby continuously encouraging further researches. In this review, recently reported plasmonic colorimetric biosensors are discussed with a focus on the following categories: (i) on-platform-based (localized surface plasmon resonance, coupled plasmon resonance and surface lattice resonance); (ii) colloid aggregation-based (label-based and label free); (iii) colloid non-aggregation-based (nanozyme, etching-based and growth-based).

【 授权许可】

Unknown