Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report

Malaysian Orthopaedic Journal

Gill R¹  Low TC¹  Saw KY² 

[1] FRCS;MCh Orth;

关键词: massive bone loss;    bone regeneration;    bone healing index;    peripheral blood stem cells;    ilizarov;   

DOI  :  10.5704/MOJ.2011.026

来源: DOAJ

【 摘 要 】

This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated bony fragments were removed and infected bone resected. Soft tissue coverage and antibiotics were effective against the MRSA infection. A unifocal bone transport with the Ilizarov method regenerated 13cm of the missing tibia. Autologous peripheral blood stem cells (PBSC) injections into the osteogenesis site boosted bone regeneration and consolidation with a shortened Bone Healing index (BHI) of 23 days/cm.

【 授权许可】

Unknown