Microfluidic biosensing of circulating tumor cells (CTCs): Recent progress and challenges in efficient diagnosis of cancer

Biomedicine & Pharmacotherapy

Mohammad Hasanzadeh¹  Fatemeh Farshchi² 

[1] Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;

关键词: Cancer;    Nanobiomedicine;    Microfluidic;    Biosensing;    Circulating tumor cells (CTCs);    Biomedical analysis;   

DOI  :  

来源: DOAJ

【 摘 要 】

Cancer metastasis is one of the foremost causes of cancer incidence and fatality in the whole of the world. Circulating tumor cells (CTC) have been confirmed to be among the most significant stimuli of metastasis in recent years and presently are the subject of extensive research aiming to be accurately identified by using biological and physical properties. Among the various studies conducted for isolation, identification, and characterization of CTCs, microfluidic systems have aroused great attention owing to their unique advantages such as low-cost, simplicity, reduction in reagent consumption, miniaturization, fast and precise control. The purpose of this review is to provide an overview of current state of the microfluidic biosensors for the screening of CTCs. Additionally, given the recent progress in this field, future outlook for the development of the microfluidics biosensing is briefly discussed.

【 授权许可】

Unknown