Evaluating health related quality of life in outpatients receiving anti-cancer treatment: results from an observational, cross-sectional study

Health and Quality of Life Outcomes

Hae-Jin Suh Oh¹  Ángeles Flórez Menéndez¹  Lucía Vilanova-Trillo¹  Víctor Sacristán Santos²  Ángeles Rodríguez Martínez³  Manuel Constenla Figueiras³  Francisca Fernández Ribeiro⁴  Manuel Pereiro Ferreiros⁵ 

[1] Dermatology Department, Pontevedra University Hospital;Medical Oncology Department, A Coruña University Hospital;Medical Oncology Department, Pontevedra University Hospital;Pharmacy Department, Pontevedra University Hospital;Surgical Medical Specialties Department, Dermatology Section, Santiago de Compostela University;

关键词: Cancer;    Cutaneous adverse events;    Targeted therapies;    Patient-reported outcomes;    FACT-G;    Quality of life;   

DOI  :  10.1186/s12955-021-01876-9

来源: DOAJ

【 摘 要 】

Abstract Background The aim of the study was to assess health-related quality of life (HRQOL) in outpatients receiving anti-cancer treatment. Methods Observational, cross-sectional, single-center study that assessed HRQOL in cancer patients receiving antineoplastic treatment. Results A total of 184 patients were included in the study; the median total FACT-G score was 66 ± 12.9; the scores for the physical well-being, social/family well-being, emotional well-being and functional well-being domains were 17.8 + 4.8, 19.1 ± 4.4, 14.8 ± 3.8 and 14.3 ± 4.7 respectively. Patients with adverse events had poorer HRQOL compared to those without them (FACT-G score 62.2 vs. 67.3; p < 0.05). In the multivariate analysis the variables associated with poorer HRQOL in the form of a gradient were tumor stage and performance status (ECOG); female sex was also associated with poorer HRQOL. Conclusion In our study, the neoplastic disease and anti-cancer treatment toxicities had an impact on HRQOL. Patients had poorer scores in the functional well-being domain and higher ones in the social/family well-being domain. Variables associated with worse HRQOL were tumor stage, performance status (ECOG) and female sex.

【 授权许可】

Unknown