Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating

Journal of Functional Biomaterials

关键词: cancer therapy;    ablation treatment;    high-frequency induction heating;    AC magnetic field;    shape magnetic anisotropy;    magnetic flux direction;    biocompatibility;   

DOI  :  10.3390/jfb3010163

来源: DOAJ

【 摘 要 】

To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.

【 授权许可】

Unknown