Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating

Journal of Functional Biomaterials

Takashi Naohara³  Hiromichi Aono³  Tsunehiro Maehara³  Hideyuki Hirazawa²  Shinya Matsutomo¹ 

[1] Department of Electronic Control Engineering, Niihama National College of Technology, Niihama 792-8580, Japan; E-Mail:;Department of Environmental Materials Engineering, Niihama National College of Technology, Niihama 792-8580, Japan; E-Mail:;Graduate School of Science and Engineering, Ehime University, Matsuyama 790-8577, Japan; E-Mails:

关键词: cancer therapy;    ablation treatment;    high-frequency induction heating;    AC magnetic field;    shape magnetic anisotropy;    magnetic flux direction;    biocompatibility;   

DOI  :  10.3390/jfb3010163

来源: mdpi

【 摘 要 】

To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.