A case report of liver transplantation following a biliopancreatic diversion: A friendly cohabitation?

Transplantation Reports

Madleen Chassang¹  Lidia Santarpia²  Rodolphe Anty³  Jean Gugenheim⁴  Anne-Sophie Schneck⁵  Antonio Iannelli⁶  Sébastien Frey⁶ 

[1] Corresponding author at: Digestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, 151 Route de Saint-Antoine, Archet 2 Hospital, Nice, France.;Digestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, Archet 2 Hospital, Nice, France;Diagnostic Radiology Unit, Centre Hospitalier Universitaire de Nice, Archet 2 Hospital, Nice, France;Digestive Surgery Unit, Centre Hospitalier Universitaire de Guadeloupe, Pointe-à-Pitre, Guadeloupe;Internal Medicine and Clinical Nutrition, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy;Université Côte d'Azur, Nice, France;

关键词: Liver transplantation;    Hepatocellular carcinoma;    Duodenal switch;    Bariatric surgery;   

DOI  :  

来源: DOAJ

【 摘 要 】

Today, bariatric surgery has become the main therapeutic means to fight against the escalating increase in obesity, worldwide. Besides that, non-alcoholic steatohepatitis has inflated its indication for liver transplantation. Liver transplant surgeons are prone to face more and more patients with such background. Here, we described the first case of liver transplantation for hepatocellular carcinoma in a patient with previous history of biliopancreatic diversion with duodenal switch. Biliopancreatic diversion with duodenal switch is nowadays an uncommon bariatric surgery but use to be a second stage surgery following sleeve gastrectomy. Liver transplantation can be challenging as such bariatric procedure reshape the digestive anatomy and can also be responsible for malnutrition. Without such complication and in a center specialized in bariatric surgery and liver transplantation, such cases can be successful and should not alarm liver transplant surgeons. In our case, the bariatric anatomy was conserved, and the liver transplantation was successful, without difficulty of the post-operative immunosuppressive treatment. However, long term follow-up showed an exacerbation of the sarcopenia level and establish even more the need for an association of a well-planned physical and nutritional rehabilitation in the peri-operative period in such candidate.

【 授权许可】

Unknown