期刊论文详细信息
Molecules | |
Microwave-Assisted Synthesis of some Novel Azoles and Azolopyrimidines as Antimicrobial Agents | |
Mohie E. M. Zayed1  Yahia Nasser Mabkhot2  Amany M. G. Mohamed3  Thoraya A. Farghaly3  Sobhi M. Gomha3  | |
[1] Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah B.O. 208203, Saudi Arabia;Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh-11451, Saudi Arabia;Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt; | |
关键词: thiophenes; pyrazoles; thiazoles; antimicrobial activity; microwave irradiation; | |
DOI : 10.3390/molecules22030346 | |
来源: DOAJ |
【 摘 要 】
In this study, new derivatives of pyrazole, isoxazole, pyrazolylthiazole, and azolopyrimidine having a thiophene ring were synthesized under microwave irradiation. Their pharmacological activity toward bacteria and fungi inhibition was screened and compared to the references Chloramphenicol and Trimethoprim/sulphamethoxazole. The antimicrobial results of the investigated compounds revealed promising results and some derivatives have activities similar to the references used.
【 授权许可】
Unknown