“Mendelian Randomization” Approach in Economic Assessment of Health Conditions

Frontiers in Public Health

Vipin Gupta¹  Mohinder P. Sachdeva¹  Gagandeep Kaur Walia² 

[1] Department of Anthropology, University of Delhi, New Delhi, India;Public Health Foundation of India, Gurugram, India;

关键词: health economics;    Mendelian randomization;    genes;    epidemiology;    public health;   

DOI  :  10.3389/fpubh.2019.00002

来源: DOAJ

【 摘 要 】

The increased prevalence of non-communicable chronic diseases (NCDs) is reflected in the rising economic burden of health conditions. Observational studies conducted in health economics research are detecting associations of NCDs or related risk factors with economic measures like health insurance, economic inequalities, accessibility of jobs, education, annual income, health expenditure, etc. The inferences of such relationships do not prove causation and are limited to associations which are many times influenced by confounding factors and reverse causation. Mendelian randomization (MR) approach is a useful method for exploring causal relations between modifiable risk factors and measures of health economics. The application of MR in economic assessment of health conditions has been started and is producing fruitful results.

【 授权许可】

Unknown