Neuroprotective Role of Phytochemicals

Molecules

Ching-Feng Weng¹  Varadharajan Thiyagarajan²  BharathiPriya Lohanathan³  Baskaran Rathinasamy⁴  BharathKumar Velmurugan⁵ 

[1] Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan;Department of Pathology, Anatomy and Cell biology, Thomas Jefferson University, Philadelphia, PA 19107, USA;Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei 10617, Taiwan;Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10617, Taiwan;Toxicology and Biomedicine Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City 700000, Vietnam;

关键词: phytochemicals;    neurogenerative disease;    curcumin;    EGCG;    resveratrol;    limonoids;   

DOI  :  10.3390/molecules23102485

来源: DOAJ

【 摘 要 】

Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD.

【 授权许可】

Unknown