Malaria in the ‘Omics Era’

Genes

GarethD. Weedall¹  Mirko Pegoraro¹ 

[1] School of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK;

关键词: Plasmodium;    malaria;    genomics;    methylomics;    methylation;   

DOI  :  10.3390/genes12060843

来源: DOAJ

【 摘 要 】

Genomics has revolutionised the study of the biology of parasitic diseases. The first Eukaryotic parasite to have its genome sequenced was the malaria parasite Plasmodium falciparum. Since then, Plasmodium genomics has continued to lead the way in the study of the genome biology of parasites, both in breadth—the number of Plasmodium species’ genomes sequenced—and in depth—massive-scale genome re-sequencing of several key species. Here, we review some of the insights into the biology, evolution and population genetics of Plasmodium gained from genome sequencing, and look at potential new avenues in the future genome-scale study of its biology.

【 授权许可】

Unknown