Floppy iris syndrome with oral imipramine: A case series

Indian Journal of Ophthalmology

关键词: Orbit;    proptosis;    thyroid;    Hyperhomocysteinemia;    retinal arterial occlusions;    systemic associations;    young age;    Illumination;    letter charts;    visual acuity;    Dacryocystorhinostomy;    intraocular pressure;    systemic effects;    timolol maleate;    Accommodation;    dynamic retinoscopy;    ophthalmoscopy;    photorefraction;    photoretinoscopy;    Apoptosis;    corneal epithelium;    formulation;    sphingosine-1 phosphate;    Digital camera;    external photograph;    photography;    Android;    eye handbook;    iPhone;    smart phone;    testing tools;    Anterior chamber intraocular lens;    gyrate atrophy;    posterior dislocation of intraocular lens;    psuedophakia;    Conjunctival ulcer;    conjunctivitis;    Stenotrophomonas maltophilia;    Adrenergic blocker;    imipramine;    intraoperative floppy iris syndrome;    iris hooks;    phacoemulsification;   

DOI  :  10.4103/0301-4738.94057

来源: DOAJ

【 摘 要 】

Intraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy. The three patients took imipramine for 25 years, 10 months and 1 year, respectively. However, only the first patient was on oral therapy at the time of surgery, while the other two patients had stopped 4 months and 2 months prior to undergoing phacoemulsification. The first and third patients developed complete IFIS features, while the second had only partial IFIS characteristics. Phacoemulsification could be completed in all three patients without any complication. None of these patients had history of taking any of the α1-adrenoceptor blocking agents. This is the first anecdotal report of IFIS with the oral use of imipramine and hence further evidences are required to ascertain the association of oral imipramine therapy and IFIS. However, ophthalmologists undertaking phacoemulsification on patients on imipramine therapy should be alert for the occurrence of IFIS.

【 授权许可】

Unknown