Secondary prevention of sudden cardiac death

Heart Rhythm O2

Thomas D. Rea, MD, MPH¹  Neal A. Chatterjee, MD, MSc² 

[1] Address reprint requests and correspondence: Dr Neal A. Chatterjee, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195.;Electrophysiology Section, Cardiology Division, University of Washington, Seattle, Washington;

关键词: Cardiac arrest;    Epidemiology;    Implantable cardioverter-defibrillator;    Prevention;    Sudden death;    Ventricular arrhythmia;   

DOI  :  

来源: DOAJ

【 摘 要 】

The prevention and treatment of sudden cardiac death (SCD) remains a significant public health challenge. For patients with a history of sudden death attributable to ventricular arrhythmia, implantable cardioverter-defibrillator (ICD) therapy is a mainstay of treatment, although these patients remain at high risk for recurrent ventricular arrhythmia and defibrillator therapies. In this review, we summarize landmark clinical trials evaluating the efficacy of ICD therapy in secondary prevention patients, review clinical outcomes including mode of death in survivors of SCD, and highlight the role for systematic diagnostic evaluation. We additionally discuss the invasive electrophysiological management of these patients, including ICD selection and programming as well as the role and timing of antiarrhythmic drug therapy and catheter ablation. Finally, we frame future challenges and needs to advance the care for secondary prevention patients.

【 授权许可】

Unknown