The effect of low level laser irradiation on oxidative stress, muscle damage and function following neuromuscular electrical stimulation. A double blind, randomised, crossover trial

BMC Sports Science, Medicine and Rehabilitation

Maciej Płaszewski¹  Tomasz Sacewicz²  Marta Jarocka²  Maciej Cieśliński³  Ewa Jówko³  Igor Cieśliński³ 

[1] Faculty of Physical Education and Health in Biała Podlaska, Chair of Natural Sciences;Faculty of Physical Education and Health in Biała Podlaska, Chair of Rehabilitation;Józef Piłsudski University of Physical Education in Warsaw;

关键词: Photobiomodulation;    Evoked contractions;    Exercise-induced muscle damage;    Biochemistry;    DOMS;    Knee extensors;   

DOI  :  10.1186/s13102-019-0147-3

来源: DOAJ

【 摘 要 】

Abstract Background Low level laser therapy (LLLT) is among novel methods for preventing and treating muscle damage and soreness induced by volitional exercise, but little is known about using LLLT before neuromuscular electrical stimulation. The aim of this first randomised, double blind, crossover trial addressing this issue was to evaluate effects of LLLT on muscle damage and oxidative stress, as well as recovery of muscle function after a single session of isometric neuromuscular electrical stimulation(NMES). Methods Twenty four moderately active, healthy men aged 21–22 years received 45 electrically evoked tetanic, isometric contractions of the quadriceps femoris, preceded by LLLT or sham-LLLT. Maximal isometric voluntary muscle torques, perceived soreness, and blood samples were analysed from baseline to 96 h post intervention. We measured plasma markers of muscle damage (the activity of creatine kinase), and inflammation (C-reactive protein), and evaluated redox state parameters. Results NMES-evoked contractions induced oxidative stress, demonstrated by an increase in lipid peroxidation and impairments in enzymatic antioxidant system. LLLT irradiations had a protective effect on NMES-induced decrease in enzymatic antioxidant defence and shortened the duration of inflammation. This effect of irradiations on redox state and inflammation did not affect lipid peroxidation, muscle damage, and muscle torque. Conclusions LLLT may protect from impairments in enzymatic antioxidant system and may shorten inflammation induced by a single NMES session in moderately active, healthy men. However, the effects of LLLT on redox state and inflammatory processes do not seem to affect muscle damage and recovery of muscle function after NMES. Trial registration The study was retrospectively registered in the Australian New Zealand Clinical Trials Registry (ANZCTR); The trial registration number: ACTRN12619000678190; date of registration: 6 May 2019.

【 授权许可】

Unknown