Impact of Different Metal Artifact Reduction Techniques on Attenuation Correction of Normal Organs in 18F-FDG-PET/CT

Diagnostics

Martin Sedlmair¹  Lino M. Sawicki²  Gerald Antoch²  Johannes Boos²  Ole Martin²  Katrin Wingendorf²  Janna Morawitz²  Eduards Mamlins³  Christina Antke³  Benedikt M. Schaarschmidt⁴ 

[1] Department of Computed Tomography, Siemens Healthineers GmbH, D-91301 Forchheim, Germany;Department of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany;Department of Nuclear Medicine, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany;Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, D-45147 Essen, Germany;

关键词: positron emission tomography/computed tomography;    artifacts;    image processing;    computer-assisted;   

DOI  :  10.3390/diagnostics12020375

来源: DOAJ

【 摘 要 】

Purpose: To evaluate the impact of different metal artifact reduction algorithms on Hounsfield units (HU) and the standardized uptake value (SUV) in normal organs in patients with different metal implants. Methods: This study prospectively included 66 patients (mean age of 66.02 ± 13.1 years) with 87 different metal implants. CT image reconstructions were performed using weighted filtered back projection (WFBP) as the standard method, metal artifact reduction in image space (MARIS), and an iterative metal artifacts reduction (iMAR) algorithm for large implants. These datasets were used for PET attenuation correction. HU and SUV measurements were performed in nine predefined anatomical locations: liver, lower lung lobes, descending aorta, thoracic vertebral body, autochthonous back muscles, pectoral muscles, and internal jugular vein. Differences between HU and SUV measurements were compared using paired t-tests. The significance level was determined as p = 0.017 using Bonferroni correction. Results: No significant differences were observed between reconstructed images using iMAR and WFBP concerning HU and SUV measurements in liver (HU: p = 0.055; SUVmax: p = 0.586), lung (HU: p = 0.276; SUVmax: p = 1.0 for the right side and HU: p = 0.630; SUVmax: p = 0.109 for the left side), descending aorta (HU: p = 0.333; SUVmax: p = 0.083), thoracic vertebral body (HU: p = 0.725; SUVmax: p = 0.392), autochthonous back muscles (HU: p = 0.281; SUVmax: p = 0.839), pectoral muscles (HU: p = 0.481; SUVmax: p = 0.277 for the right side and HU: p = 0.313; SUVmax: p = 0.859 for the left side), or the internal jugular vein (HU: p = 0.343; SUVmax: p = 0.194). Conclusion: Metal artifact reduction algorithms such as iMAR do not alter the data information of normal organs not affected by artifacts.

【 授权许可】

Unknown