Treatment of colon cancer in a patient with systemic lupus erythematosus: a case report

BMC Cancer

Qing Chang¹  Qingqing Yi¹  Lijuan Shen²  Boshun Wan³  Jianquan Fei³  Yueyu Chen³  Junfeng Shi⁴ 

[1] Clinical Research Center, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences;Department of Clinical Laboratory, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences;Department of General Surgery, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences;Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences;

关键词: Systemic lupus erythematosus;    Colon cancer;    Radical resection;    Prednisone;    Methylprednisolone;   

DOI  :  10.1186/s12885-018-4864-x

来源: DOAJ

【 摘 要 】

Abstract Background Gastrointestinal symptoms occur in approximately 50% of patients with systemic lupus erythematous with low specificity. Although it is well established that colon cancer is one of the many gastrointestinal manifestations associated with systemic lupus erythematous, the diagnosis and treatment remains complex due to adrenal insufficiency symptoms. Case presentation A 43-year-old Chinese woman with a five-year history of systemic lupus erythematous was diagnosed with colon cancer based on imaging test. A radical bowel resection was performed successfully. To avoid serious complications during surgery, prednisone was replaced with methylprednisolone therefore avoiding adrenal insufficiency. The patient was subsequently treated with mFOLFOX6 chemotherapy and recovered well. Conclusion There is a lack of reports for treatment of colon cancer in patients with systemic lupus erythematous. This report provides an effective way to diagnose colon cancer in patients with systemic lupus erythematous and illustrates a successful therapy strategy for this complex medical condition.

【 授权许可】

Unknown