Larvicidal activity of marine algae, Sargassum swartzii and Chondria dasyphylla, against malaria vector Anopheles stephensi

Journal of Vector Borne Diseases

关键词: Anopheles stephensi;    Chondria dasyphylla;    Iran;    larvicidal activity;    Sargassum swartzii;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objectives: The objective of this study was to evaluate larvicidal activity of native marine algae against mainmalaria vector Anopheles stephensi.Study design: The total 70% methanol (MeOH) extract and partition fractions of chloroform (CHCl3), ethylacetate(EtOAc), and MeOH from two algae, Sargassum swartzii and Chondria dasyphylla were investigated for larvicidalactivities against late III and early IV instar larvae of malaria vector An. stephensi.Results: Among all the fractions tested against larvae, EtOAc fraction of S. swartzii and C. dasyphylla, showedmortality rate of 96 and 95%, respectively. Probit analysis of logarithmic concentration from regression lineexhibited the LC50 and LC90 values of 11.75 and 53.47 ppm respectively for S. swartzii and 10.62 and 56.39 ppmrespectively for C. dasyphylla.Conclusion: This is the first report of larvicidal activities of two native algae against An. stephensi. We proposethat the larvicidal activity of EtOAc fraction is related to the presence of semi-polar compounds. Further isolationand purification could lead to identify more potent compounds.

【 授权许可】

Unknown