Indonesian Journal of Pharmacy | |
The effect of fumaric acid-sodium bicarbonate on the green tea effervescent granule’s quality made by dry granulation | |
Maria Yuli Trisusilawati1  Agatha Busi susiati Lestari1  | |
[1] Fakultas Farmasi Universitas Sanata Dharma Yogyakarta; | |
关键词: green tea; fumaric acid; effervescent granule; dry granulation; | |
DOI : http://dx.doi.org/10.14499/indonesianjpharm0iss0pp218-224 | |
来源: DOAJ |
【 摘 要 】
Tea plant (CamelliasinensisL.)had beenknowntocontains epigallocathecin gallate (EGCG) that can be used to maintain the healthy. In this research, the green tea wastried to be formulated in effervescent dosage form, withthefocusontheeffectamongfumaricacid,sodiumbicarbonate,andthe interactionbetweenfumaricacidandsodiumbicarbonateonthegreentea extracteffervescent granule’sphysical properties, that made by dry granulation method.Physicalpropertiesofeffervescentgranulethatbeenstudywere moisturecontent,flowrate,disintegrationtime,andpHofthesolution.The result showed that sodium bicarbonate was dominant in determining pH, granule flowrateandmoisturecontentofgranule,whereasfumaricaciddominantin disintegration time of effervescent granule.
【 授权许可】
Unknown