What triggers inflammation in COVID-19?

eLife

Takaaki Akaike¹  Tomohiro Sawa² 

[1] Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan;Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan;

关键词: SARS-CoV-2;    COVID-19;    spike protein;    cytokine storm;    TLR2;    inflammation;   

DOI  :  10.7554/eLife.76231

来源: DOAJ

【 摘 要 】

The spike protein of SARS-CoV-2 triggers macrophages and epithelial cells to produce excess levels of pro-inflammatory molecules, which can do more harm than good.

【 授权许可】

Unknown