期刊论文详细信息
Engineering in Life Sciences
Simultaneous use of sodium nitrate and urea as nitrogen sources improves biomass composition of Arthrospira platensis cultivated in a tubular photobioreactor
Ana Lucía Morocho‐Jácome1  Laís deLara Capurro Guimarães1  Camila Knysak Camargo deJesus1  João Carlos Monteiro deCarvalho1  Sunao Sato1 
[1] Department of Biochemical and Pharmaceutical Technology Faculty of Pharmaceutical Sciences, University of São Paulo São Paulo Brazil;
关键词: Arthrospira (Spirulina) platensis;    Biomass composition;    Sodium nitrate;    Tubular photobioreactor;    Urea;   
DOI  :  10.1002/elsc.201500051
来源: DOAJ
【 摘 要 】

Arthrospira platensis is widely cultivated in open ponds for industrial purposes. However, high‐protein A. platensis biomass produced in photobioreactors (PBRs) is recommended for pharmaceutical and cosmetic formulations. A. platensis was cultivated in a 3.5 L tubular airlift PBR using both sodium nitrate and urea as nitrogen sources. Sodium nitrate was added from the start of the cultivation using a batch process. Urea was supplied daily at exponentially increasing feeding rate using a fed‐batch process. The simultaneous optimization of the independent variables, namely, total quantity of sodium nitrate (mT1) and total quantity of urea (mT2), led to an optimal condition of mT1 = 15.0 mmol/L and mT2 = 7.5 mmol/L. Maximum biomass concentration (5183 ± 94 mg/L) corresponding to the highest biomass productivity (683 ± 13 mg/L/day) was obtained under such condition. The addition protocol of both nitrogen sources resulted in high productivities of protein (6.2 ± 0.4 mg/L/day) as well as chlorophyll‐a (372.2 ± 7.7 mg/L/day). Such innovative process could be applied in the large‐scale production of A. platensis using tubular PBR for novel applications.

【 授权许可】

Unknown   

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