Lactobacillus plantarum PL-02 Supplementation Combined With Resistance Training Improved Muscle Mass, Force, and Exercise Performance in Mice

Frontiers in Nutrition

Wen-Ling Yeh¹  Hsieh-Hsun Ho³  Shin-Yu Tsai³  Yi-Wei Kuo³  Chi-Chang Huang⁴  Mon-Chien Lee⁴  Yi-Ju Hsu⁴  Chin-Shen Ho⁴ 

[1] Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan;Department of Orthopedic Surgery, Lotung Poh-Ai Hospital, Luodong, Taiwan;Department of Research and Design, Bioflag Biotech Co., Ltd., Tainan, Taiwan;Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan, Taiwan;

关键词: Lactobacillus plantarum PL-02;    probiotic;    muscle mass;    exercise;    training;   

DOI  :  10.3389/fnut.2022.896503

来源: DOAJ

【 摘 要 】

Increasing numbers of researchers are investigating the benefits of probiotics in enhancing exercise performance and verifying the role of the gut–muscle axis. In our previous study, Lactobacillus plantarum PL-02 improved exercise performance and muscle mass. Therefore, the purpose of this study was to investigate whether supplementation with PL-02 combined with resistance training has a synergistic effect on exercise performance and muscle mass. All the animals were assigned into four groups (n = 8/group): a sedentary control with normal distilled water group (vehicle, n = 8); PL-02 supplementation group (PL-02, 2.05 × 109 CFU, n = 8); resistance training group (RT, n = 8); PL-02 supplementation combined with resistance training group (PL-02 + RT, 2.05 × 109 CFU, n = 8). Supplementation with PL-02 for four consecutive weeks combined with resistance exercise training significantly improved the grip strength and the maximum number of crawls; increased the time of exhaustive exercise; significantly reduced the time required for a single climb; and reduced the lactate, blood ammonia, creatine kinase, and blood urea nitrogen produced after exercise (p < 0.05). In addition, it produced substantial benefits for increasing muscle mass without causing any physical damage. In summary, our findings confirmed that PL-02 or RT supplementation alone is effective in improving muscle mass and exercise performance and in reducing exercise fatigue, but the combination of the two can achieve increased benefits.

【 授权许可】

Unknown