Anti-Melanoma Capability of Contactless Cold Atmospheric Plasma Treatment

International Journal of Molecular Sciences

Qihui Wang¹  Xiaoliang Yao¹  Dayun Yan¹  Alisa Malyavko²  Michael Keidar² 

[1] Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA;School of Medicine and Health Science, George Washington University, Washington, DC 20052, USA;

关键词: melanoma treatment;    cold plasma;    non-invasive;    contactless treatment;   

DOI  :  10.3390/ijms222111728

来源: DOAJ

【 摘 要 】

In this study, we demonstrated that the widely used cold atmospheric plasma (CAP) jet could significantly inhibit the growth of melanoma cells using a contactless treatment method, The flow rate of helium gas was a key operational parameter to modulate electromagnetic (EM) effect on melanoma cells. Metal sheets with different sizes could be used as a strategy to control the strength of EM effect. More attractive, the EM effect from CAP could penetrate glass/polystyrene barriers as thick as 7 mm. All these discoveries presented the profound non-invasive nature of a physically based CAP treatment, which provided a solid foundation for CAP-based cutaneous/subcutaneous tumor therapy.

【 授权许可】

Unknown