Phenolic Compounds from Five Ericaceae Species Leaves and Their Related Bioavailability and Health Benefits

Molecules

Gianina Crişan¹  BiancaEugenia Ștefănescu¹  Andrei Mocan¹  Katalin Szabo² 

[1] Department of Pharmaceutical Botany, “Iuliu Hațieganu” University of Medicine and Pharmacy, 23, Ghe. Marinescu Street, 400337 Cluj-Napoca, Romania;Institute of Life Sciences, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, CaleaMănăştur 3-5, 400372 Cluj-Napoca, Romania;

关键词: Ericaceae;    Vaccinium spp. leaves;    phenolic components;    arbutin;    chlorogenic acid;    quercetin;   

DOI  :  10.3390/molecules24112046

来源: DOAJ

【 摘 要 】

Some species of the Ericaceae family have been intensively studied because of the beneficial health impact, known since ancient times, of their chemical components. Since most studies focus on the effects of fruit consumption, this review aims to highlight the phenolic components present in the leaves. For this purpose, five species from Ericaceae family (bilberry—Vaccinium myrtillus L., lingonberry—V. vitis-idaea L., bog bilberry—V. uliginosum L., blueberry—V. corymbosum L. and bearberry—Arctostapylos uva-ursi L.) were considered, four of which can be found in spontaneous flora. The chemical composition of the leaves revealed three major phenolic compounds: chlorogenic acid, quercetin and arbutin. The health promoting functions of these compounds, such as antioxidant and anti-inflammatory properties that could have preventive effects for cardiovascular disease, neurodegenerative disorders, cancer, and obesity, have been exemplified by both in vitro and in vivo studies in this review. Furthermore, the importance of bioaccessibility and bioavailability of the phenolic compounds have been summarized. The findings highlight the fact that leaves of some Ericaceae species deserve increased attention and should be studied more profoundly for their biological activities, especially those from spontaneous flora.

【 授权许可】

Unknown