Higher Appendicular Skeletal Muscle Mass Protects Metabolically Healthy Obese Boys but Not Girls from Cardiometabolic Abnormality

International Journal of Environmental Research and Public Health

Seung-Nam Kim¹  Jaehee Kim² 

[1] College of Korean Medicine, Dongguk University, Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 10326, Korea;Graduate School of Alternative Medicine, Kyonggi University, 63, Kyonggidae-ro 9-gil, Seodaemun-gu, Seoul 120-837, Korea;

关键词: obesity;    skeletal muscle mass;    adolescent;    gender difference;    cardiometabolic abnormalities;   

DOI  :  10.3390/ijerph16040652

来源: DOAJ

【 摘 要 】

Factors related to metabolically healthy obesity (MHO) are not well characterized in adolescents. The study’s aim was to investigate the impact of skeletal muscle mass (SMM) on MHO in adolescents. A secondary analysis was performed using the data of 221 Korean overweight and obese adolescents aged 12⁻18 years from the Korean National Health and Nutrition Examination Survey. Appendicular skeletal muscle (ASM) mass and total body fat mass were measured by dual-energy X-ray absorptiometry. Being metabolically unhealthy was defined using three definitions: Having ≥1, ≥2, or ≥3 cardiometabolic risk factors (CRFs; waist circumference, blood pressure, glucose, triglycerides, and HDL-cholesterol). Multiple logistic regression analyses adjusted for age and lifestyle factors were performed to assess the association between ASM and MHO. In boys, the risk for having either ≥2 CRFs or ≥3 CRFs was significantly lower with higher weight-adjusted ASM and ratio of ASM to fat mass after controlling for covariates, but this association was not significant with CRFs ≥ 1. In girls, all adjusted odds ratios were not significant. Findings indicate that SMM is a potentially protective factor against cardiometabolic abnormality in adolescents with MHO, showing gender difference. This heightens the importance of SMM in the management of obesity, especially in boys.

【 授权许可】

Unknown