Reliability of foveal avascular zone measurements in eyes with retinal vein occlusion using optical coherence tomography angiography

International Journal of Retina and Vitreous

Alexandre Gomes Bortoloti de Azevedo¹  Somaia Mitne¹  Flavio Eduardo Hirai¹  Luis Filipe Nakayama¹  Bruno Mauricio Rodrigues de Oliveira¹  Bruno Rebello de Godoy¹ 

[1] Retina and Vitreous Sector, Department of Ophthalmology, Universidade Federal de São Paulo – Escola Paulista de Medicina;

关键词: Retina;    Foveal avascular zone;    OCT;    Retinal vein occlusion;   

DOI  :  10.1186/s40942-020-00237-w

来源: DOAJ

【 摘 要 】

Abstract Background To evaluate the reliability of foveal avascular zone (FAZ) area measurements using optical coherence tomography angiography (OCTA) in eyes with retinal vein occlusion (RVO). Methods Twenty-five OCTA exams of patients with RVO were evaluated retrospectively. Three examiners performed manual measurements of the FAZ, and interrater and intrarater reliability were obtained. Results The intraclass correlation coefficient (ICC) for interrater reliability for individual measurements was 0.62 (moderate) with a 95% confidence interval (CI) of 0.40 to 0.79 (p < 0.001). The ICC (95% CI) for intrarater reliability was 0.92 (0.82 to 0.96) for rater A, 0.96 (0.91 to 0.98) for B, and 0.88 (0.76 to 0.94) for C (p < 0.001). In all subanalyses including presence of edema and type of occlusion, interrater reliability was poor/moderate, and intrarater reliability was good/excellent. Conclusion The FAZ varies significantly among eyes with RVO, so measurements obtained using OCTA should be analyzed with caution due to the moderate level of reliability among different examiners.

【 授权许可】

Unknown