New potential and characterization of Andrographis paniculata L. Ness plant extracts as photoprotective agent

Arabian Journal of Chemistry

Taslim Ersam¹  Agus Slamet²  Suprapto³  Fredy Kurniawan⁴  Qonitah Fardiyah⁴  Suyanta⁵ 

[1]Analytical Chemistry Laboratory, Departement of Chemistry, Faculty of Mathematic and Natural Science, Brawijaya University, Malang 65145, Indonesia

[2]Analytical Chemistry Laboratory, Department of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Indonesia

[3]Department of Environmental Engineering, Faculty of Civil, Planning, and Geo Engineering, Institut Teknologi Sepuluh Nopember, Surabaya 6011, Indonesia

[4]Instrumentation and Analytical Sciences Laboratory, Department of Chemistry, Faculty of Sciences, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia

[5]Natural Products and Synthesis Chemistry Research Laboratory, Department of Chemistry, Faculty of Sciences, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia

关键词: Herbal plant;    Sambiloto;    Ethanolic extracts;    UV protector;    SPF;   

DOI  :  

来源: DOAJ

【 摘 要 】

The species Andrographis paniculata L. Ness, family Acanthaceae grows in many parts in the island of Java in Indonesia. In this research, new potentials of photoprotective agents from A. paniculata plant extracts, along with their characteristics, were investigated. The phytochemical test, infrared analysis, ultraviolet characterization, fluorescence identification, flavonoid content by thin layer chromatography, high performance liquid chromatography-mass spectrometry (LCMS/MS) and photoprotective analysis were performed in the extracts. The new potentials of A. paniculata plant extracts were studied at various concentrations of extracts and shown by the value of the sun protection factor (SPF). Based on phytochemical test, A. paniculata plant extracts contained flavonoids, alkaloids, tannins, triterpenoids and polyphenols. A. paniculata plant extracts have 2 maximum wavelengths at 230 nm and 362 nm. The excitation peak at 300 nm (552.11 a.u) and the emission peak at 605 nm (516.02 a.u). The flavonoid content of the extracts was 0.022 µg/mL quercetin with Rf value of 0.61. The chromatogram of the LCMS/MS is similar to quercetin-3-glycoside standard at a retention time of 2.77. The photoprotective activity of A. paniculata plant extracts had ≥ 15 SPF. Its shows the possibility to use this extract as photoprotective agent in pharmaceutical preparations.

【 授权许可】

Unknown