A convenient and efficient synthesis of 2-thio-5-hydroxy-5H-[1]benzopyrano[4,3-d] pyrimidines via ultrasonic irradiation compared with conventional method

Current Research in Green and Sustainable Chemistry

Navanath R. Dalvi¹  Satish B. Kale²  Namdeo T. Dhokale²  Sadashiv S. Nagre²  Shankaraiah G. Konda² 

[1]Corresponding author.

[2]Department of Chemistry, K. J. Somaiya College of Arts, Commerce and Science, Savitribai Phule Pune University, Kopargaon, Ahmednagar, Maharashtra, 423601, India

关键词: Synthesis;    Efficient;    Ultrasonic irradiation;    3-Formylchromone;    Conventional heating;   

DOI  :  

来源: DOAJ

【 摘 要 】

We report an easy and powerful approach to the synthesis of 2-thio-5-hydroxy-5H-[1]benzopyrano[4,3-d] pyrimidines derivatives by condensation of 3-Formylchromone and thiourea under conventional heating and ultrasonic irradiation. The ultrasonic irradiation is convenient and efficient method as compared to conventional heating in alcoholic KOH. This method affords the desired product with good to excellent yields. The IR, 1H NMR and mass spectroscopy were obtained for selected synthesized products.

【 授权许可】

Unknown