Reactions of 3-Formylchromone with Active Methylene and Methyl Compounds and Some Subsequent Reactions of the Resulting Condensation Products.

Molecules

Renata Gašparová¹ 

[1] Department of Chemistry, Faculty of Natural Sciences, University of St. Cyril and Methodius, Námestie Jozefa Herdu 2, SK-917 01 Trnava, Slovak Republic; Tel.: [phone], Fax: [phone]

关键词: 3-Formylchromone;    Knoevenagel condensation;    active  methylene compound;    active methyl compound;    microwave irradiation;    biological activity.;   

DOI  :  10.3390/10080937

来源: mdpi

【 摘 要 】

This review presents a survey of the condensations of 3-formylchromone with various active methylene and methyl compounds, e.g. malonic or barbituric acid derivatives, five-membered heterocycles, etc.  The  utilisation  of  the  condensation products for the synthesis of different heterocyclic systems, which is based on the ability of the γ-pyrone ring to be opened by the nucleophilic attack is also reviewed. Finally, the applications of microwave irradiation as an unconventional method of reaction activation in the synthesis of condensation products is described and the biological activity of some chromone derivatives is noted.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).