Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes

Beilstein Journal of Organic Chemistry

Dmitrii A. Aksenov¹  Nikolai A. Arutiunov¹  Vladimir V. Maliuga¹  Alexander V. Aksenov¹  Michael Rubin¹ 

[1] Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol 355017, Russian Federation;

关键词: cyclization;    heterocycles;    imidazo[1,5-a]pyridines;    nitroalkanes;    polyphosphoric acid;   

DOI  :  10.3762/bjoc.16.239

来源: DOAJ

【 摘 要 】

Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium.

【 授权许可】

Unknown