Crystal structure and Hirshfeld surface analysis of 3-(hydroxymethyl)-3-methyl-2,6-diphenylpiperidin-4-one

Acta Crystallographica Section E: Crystallographic Communications

Gulzhamal Bagitovna Tulemisova¹  Eiad Saif²  Necmi Dege³  Sevgi Kansiz⁴  Mustafa Kemal Gümüş⁵ 

[1] Department of Chemistry and Chemical Technologies, Faculty of Natural and Agricultural Sciences, Atyrau State University named after Kh. Dosmukhamedov, 060011, Atyrau, Kazakhstan;Department of Computer and Electronic Engineering Technology, Sanaa Community College, Sanaa, Yemen;Ondokuz Mayıs University, Faculty of Arts and Sciences, Department of Physics, 55139, Samsun, Turkey;Samsun University, Faculty of Engineering, Department of Fundamental Sciences, 55420, Samsun, Turkey;Science-Technology Research and Application Center, Artvin Coruh University, Artvin, Turkey;

关键词: crystal structure;    piperidone;    benzaldehyde;    4-hydroxy-3-methyl-2-butanone;    ammonium acetate;    hirshfeld surface;    hydrogen bonding;   

DOI  :  10.1107/S2056989021012640

来源: DOAJ

【 摘 要 】

A new synthesis of the title compound, C19H21NO2, was developed with good yield and purity using the reaction of 4-hydroxy-3-methyl-2-butanone, benzaldehyde and ammonium acetate in glacial acetic acid as a solvent. The central piperidine ring adopts a chair conformation, and its least-squares basal plane forms dihedral angles of 85.71 (11) and 77.27 (11)° with the terminal aromatic rings. In the crystal, the molecules are linked by O—H...O and C—H...O hydrogen bonds into double ribbons. The Hirshfeld surface analysis shows that the most important contributions are from H...H (68%), C...H/H...C (19%) and O...H/H...O (12%) interactions.

【 授权许可】

Unknown