Severe COVID-19 Complicated by Cerebral Venous Thrombosis in a Newborn Successfully Treated with Remdesivir, Glucocorticoids, and Hyperimmune Plasma

International Journal of Environmental Research and Public Health

Laura Cursi¹  Sara Chiurchiu¹  Laura Lancella¹  Stefania Bernardi¹  Francesca Ippolita Calo Carducci¹  Paolo Rossi¹  Lorenza Romani¹  Patrizia D’Argenio¹  Mary Haywood Lombardi²  Corrado Cecchetti²  Francesca Stoppa²  Cristina Russo³  Carlo Federico Perno³  Giulia Lucignani⁴  Daniela Longo⁴ 

[1] Academic Department of Pediatrics, Bambino Gesù Children’s Hospital—IRCCS, 00165 Rome, Italy;Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy;Department of Laboratories, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy;Imaging Department, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy;

关键词: newborn;    SARS-CoV-2;    COVID-19;    cerebral thrombosis;    remdesivir;   

DOI  :  10.3390/ijerph182413201

来源: DOAJ

【 摘 要 】

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic, affecting all age groups with a wide spectrum of clinical presentation ranging from asymptomatic to severe interstitial pneumonia, hyperinflammation, and death. Children and infants generally show a mild course of the disease, although infants have been observed to have a higher risk of hospitalization and severe outcomes. Here, we report the case of a preterm infant with a severe form of SARS-CoV-2 infection complicated by cerebral venous thrombosis successfully treated with steroids, hyperimmune plasma, and remdesivir.

【 授权许可】

Unknown