Interactions between Cytochrome c and DNA Strands Self-Assembled at Gold Electrode

International Journal of Molecular Sciences

关键词: Cytochrome c;    DNA;    electrochemistry;    gold electrodes;    cyclic voltammetry;   

DOI  :  10.3390/i8020136

来源: DOAJ

【 摘 要 】

In this work, we reported the investigation on the interaction between DNAstrands self-assembled at gold electrodes and an electron transfer protein, cytochrome c. Weobserved that cytochrome c exhibited well-defined electrochemistry in both double-strandedand single-stranded DNA films. This suggested that the electron transfer reaction ofcytochrome c arose possibly due to the electron hopping along DNA strands rather thanwiring along the double helix. We also compared the heterogeneous electron transfer rate ofcytochrome c with that of a ruthenium complex, which further confirmed this mechanism.

【 授权许可】

Unknown