Enterohepatic Helicobacter other than Helicobacter pylori

Revista Espanola de Enfermedades Digestivas

Blanca Serrano Falcón¹  Julio Pérez de la Serna¹  Beatriz Mateos Muñoz¹  Aurelio Velasco Cerrudo¹  Enrique Rey Díaz-Rubio¹  Antonio Ruiz de León¹  Sergio Casabona Francés¹ 

[1] Hospital Clínico San Carlos;

关键词: Helicobacter enterohepáticos;    Helicobacter pylori;    Helicobacter pullorum;    Helicobacter hepaticus;    Helicobacter bilis;    Hepatopatía crónica;    Enfermedad inflamatoria intestinal;    Gastroenteritis aguda;   

DOI  :  10.4321/s1130-01082013000800006

来源: DOAJ

【 摘 要 】

The Helicobacter genus includes Gram negative bacteria which were originally considered to belong to the Campylobacter genus. They have been classified in a separate genus since 1989 because they have different biochemical characteristics, with more than 24 species having been identified and more still being studied. H. pylori is the best known. It has an important etiopathogenic role in peptic ulcer disease and gastric cancer. Enterohepatic Helicobacter s (EHH) other than H. pylori colonize the bowel, biliary tree and liver of animals and human beings with pathogenic potential. The difficulties existing to correctly isolate these microorganisms limit the description of their true prevalence and of the diseases they cause. Many studies have tried to discover the different clinical implications of EHH. Diseases like chronic liver disease, autoimmune hepatitis, hepatocarcinoma, autoimmune hepatobiliary disease, biliary lithiasis, cholangiocarcinoma and gallbladder cancer, Meckel's diverticulum, acute appendicitis and inflammatory bowel disease have been related with different EHH species with different results, although their prevalence is greater than in healthy subjects. However, these data are currently not sufficient to draw definitive conclusions. Finally, the best known role of EHH in bowel disease is production of acute and chronic diarrhea pictures initially referred to as Campylobacter. H. pullorum has been identified in patients with acute gastroenteritis. The correct identification of EHH as producers of infectious gastroenteritis is found in its antibiotic susceptibility. It is generally macrolide-susceptible and quinolone-resistant.

【 授权许可】

Unknown