Human Metapneumovirus: A Largely Unrecognized Threat to Human Health

Pathogens

RhiannonR. Penkert¹  JuliaL. Hurwitz¹  CharlesJ. Russell¹  Sonnie Kim² 

[1] Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA;

关键词: respiratory virus infection;    sendai virus;    vaccine development;   

DOI  :  10.3390/pathogens9020109

来源: DOAJ

【 摘 要 】

Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no standard treatment nor licensed vaccine for HMPV, although several attractive vaccine candidates have been developed for pre-clinical studies. A raised awareness of the impact of HMPV on public health is needed to drive research, complete vaccine development, and thereby prevent significant virus-associated morbidities and mortalities worldwide.

【 授权许可】

Unknown