Influenza and Other Respiratory Viruses | |
Viral and bacterial aetiology of community‐acquired pneumonia in adults | |
Elisabeth G. W. Huijskens1  Adriana J. M. van Erkel1  Fernand M. H. Palmen1  Anton G. M. Buiting1  Jan A. J. W. Kluytmans1  | |
[1] Laboratory of Medical Microbiology and Immunology, St Elisabeth Hospital, Tilburg, The Netherlands. | |
关键词: Adults; aetiology; community‐acquired pneumonia; respiratory virus infection; viral; | |
DOI : 10.1111/j.1750-2659.2012.00425.x | |
来源: Wiley | |
【 摘 要 】
Please cite this paper as: Huijskens et al. (2012) Viral and bacterial aetiology of community-acquired pneumonia in adults. Influenza and Other Respiratory Viruses 7(4), 567–573. Background Modern molecular techniques reveal new information on the role of respiratory viruses in community-acquired pneumonia. In this study, we tried to determine the prevalence of respiratory viruses and bacteria in patients with community-acquired pneumonia who were admitted to the hospital. Methods Between April 2008 and April 2009, 408 adult patients (aged between 20 and 94 years) with community-acquired pneumonia were tested for the presence of respiratory pathogens using bacterial cultures, real-time PCR for viruses and bacteria, urinary antigen testing for Legionella and Pneumococci and serology for the presence of viral and bacterial pathogens. Results Pathogens were identified in 263 (64·5%) of the 408 patients. The most common single organisms in these 263 patients were Streptococcus pneumoniae (22·8%), Coxiella burnetii (6·8%) and influenza A virus (3·8%). Of the 263 patients detected with pathogens, 117 (44·5%) patients were positive for one or more viral pathogens. Of these 117 patients, 52 (44·4%) had no bacterial pathogen. Multiple virus infections (≥2) were found in 16 patients. Conclusion In conclusion, respiratory viruses are frequently found in patients with CAP and may therefore play an important role in the aetiology of this disease.Abstract
【 授权许可】
Unknown
© 2012 John Wiley & Sons Ltd
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202107150012954ZK.pdf | 137KB | download |