Neurodegenerative conditions: toxicity by accumulation of metals

Jounal of Negative and No Positive Results

Cecilia Martínez-Gutiérrez¹  María de Jesús Ramírez-Altamirano¹  Iván Antonio García-Montalvo²  Marco Antonio Sánchez-Medina³  Alma Dolores Pérez-Santiago⁴ 

[1] Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. México;Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Escuela de Medicina y Cirugía. Universidad Anáhuac Oaxaca. Blvd. Guadalupe Hinojosa de Murat No. 1100. C. P. 71248. San Raymundo Jalpan, Oaxaca. México;Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. Departamento de Ingeniería Química y Bioquímica. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. México;Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca. División de Estudios de Posgrado e Investigación. Instituto Tecnológico de Oaxaca. Av. Ing. Víctor Bravo Ahuja, No. 125, C. P. 68030. Oaxaca. México;

关键词: Neurodegenerative diseases;    Neurotoxicity;    Metals;   

DOI  :  10.19230/jonnpr.2944

来源: DOAJ

【 摘 要 】

Degenerative diseases of the nervous system are manifested by various syndromes. The predominant symptom is progressive dementia. These neurodegenerative conditions cause alterations in consciousness or in the nervous system leading to severe damage in neuronal cells. These pathologies are considered gradual, progressive and of varied etiology, both genetic and acquired. In thisreview, risks of toxicity are addressed and described through metals present in the day to day of thepopulation. These metals can be found in food, beverages, or in work environments, are capable of causingsevere neuronal damage in addition to induce a necrosis or apoptosis throughout the central andperipheral nervous system, which may trigger an early onset of Parkinson's Disease, Alzheimer's,Huntington's, Dementia and Amyotrophic Lateral Sclerosis, thus predisposing to increasingly youngerpopulations.

【 授权许可】

Unknown