期刊论文详细信息
Royal Society Open Science | |
An efficient synthesis of furan-3(2 |
|
Raed A. AlQawasmeh1  Ihsan A. Shehadi1  Eyad A. Younes2  Da'san M. M. Jaradat3  Anas J. Rasras3  | |
[1] College of Science, Department of Chemistry, University of Sharjah, Pure and Applied Chemistry Research Group, PO Box 27272, Sharjah, United Arab Emirates;Department of Chemistry, Faculty of Science, The Hashemite University, PO Box 330127, Zarqa 13133, Jordan;Faculty of Science, Department of Chemistry, Al-Balqa Applied University, PO Box 19117, Al-Salt, Jordan; | |
关键词: efficient; synthesis; furan-3(2H)-imine; scaffold; alkynones; authors; | |
DOI : 10.1098/rsos.211145 | |
来源: DOAJ |
【 摘 要 】
A novel efficient method to generate spiro furan-3(2H)-imine derivatives is established by the reaction between the α,β-unsaturated ketones and aniline derivatives. The reaction involves 1,4- addition of aniline followed by the subsequent intramolecular cyclization mediated by tertiary alcohol to produce the furan-3(2H)-imine. All the synthesized compounds are characterized using nuclear magnetic resonance and high-resolution mass spectrometry (HRMS).
【 授权许可】
Unknown