Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications

Polymers

NeilR. Cameron¹  Stanko Kramer²  Peter Krajnc² 

[1] Department of Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, VIC 3800, Australia;PolyOrgLab, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, Slovenia;

关键词: polyHIPE;    tissue engineering;    cell culturing;    emulsion templating;    porous polymers;    biodegradable polymers;   

DOI  :  10.3390/polym13111786

来源: DOAJ

【 摘 要 】

High internal phase emulsions (HIPEs), with densely packed droplets of internal phase and monomers dispersed in the continuous phase, are now an established medium for porous polymer preparation (polyHIPEs). The ability to influence the pore size and interconnectivity, together with the process scalability and a wide spectrum of possible chemistries are important advantages of polyHIPEs. In this review, the focus on the biomedical applications of polyHIPEs is emphasised, in particular the applications of polyHIPEs as scaffolds/supports for biological cell growth, proliferation and tissue (re)generation. An overview of the polyHIPE preparation methodology is given and possibilities of morphology tuning are outlined. In the continuation, polyHIPEs with different chemistries and their interaction with biological systems are described. A further focus is given to combined techniques and advanced applications.

【 授权许可】

Unknown